Cancer Clinical Trial - SQZ Biotechnologies - SQZ-PBMC-HPV-101

CONDITION(S): Advanced Solid Tumors - TRIAL: SQZ Biotechnologies SQZ-PBMC-HPV-101-Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

This is a Phase 1 open-label, multicenter study of the safety and tolerability, immunogenic effects, antitumor activity, and pharmacodynamics of SQZ-PBMC-HPV as monotherapy and in combination with atezolizumab in HLA-A*02+ patients with recurrent, locally advanced or metastatic human papillomavirus strain 16 positive (HPV16+) solid tumors.

Drug

Biological: SQZ-PBMC-HPV; Drug: Atezolizumab

Trial Type

Interventional

Phase

Phase 1

Condition

Advanced solid tumors Adult solid tumors

Keywords

Advanced solid tumors | SQZ-PBMC-HPV | Cellular therapies | SQZ Biotechnologies