Cancer Clinical Trial - Syros SY-1365-101

Status:

Open

ClinicalTrials.gov:

NCT03134638

CONDITION(S): Breast, ER/PR and/or Her2, Ovarian, Ovarian Clear Cell - TRIAL: Syros SY-1365-101 - A Study of SY-1365 in Adult Patients With Advanced Solid Tumors.

This study consists of two parts. Part 1 is a dose-escalation/safety evaluation to provisionally identify a dose and regimen of SY-1365 for further evaluation in Part 2.

Drug

SY-1365 (Part 1); Carboplatin; Fulvestrant; SY-1365 (Cohort 2); SY-1365 (Cohort 5); SY-1365 (Part 2 Single Agent)

Trial Type

Interventional

Condition

Breast cancer ER/PR Her2 Ovarian cancer Ovarian clear cell

Keywords

Breast cancer | ER/PR | Her2 | Ovarian cancer | Ovarian clear cell