Intercepting pancreatic cancer: An early detection/prevention program

Usually diagnosed in advanced stages, pancreatic cancer is the third leading cause of cancer-related deaths in the U.S.

Leading researchers Daniel Von Hoff, MD, and Erkut Borazanci, MD, at the HonorHealth Research Institute created an early detection screening program for those who may be at increased risk of developing the disease. Goals include:

  • Early detection of pancreatic cancer to improve long-term survival.
  • Development of new screening tests such as biomarkers for pancreatic cancer and other cancers.

The program offers a personalized approach to pancreatic cancer risk assessment through routine evaluations, diagnostics and long-term surveillance. The research team:

  • Collaborates closely with community healthcare providers.
  • Ensures that participants are monitored by a collaborative, multidisciplinary team.
  • Is contributing to the research needed to establish guidelines, which currently do not exist, for screening and early detection of pancreatic cancer.
  • Is developing innovative tools to identify pancreatic cancer early — before symptoms occur.

Referral criteria

The study will closely monitor participants for many years. You may be eligible if:

  • One or more of your family members have been diagnosed with pancreatic cancer.
  • You have a known genetic mutation that may increase your risk of developing pancreatic cancer.
  • You have been diagnosed with a pancreatic cyst, known as an intraductal papillary mucinous neoplasm (IPMN).

If you're eligible for the pancreatic cancer study, you may undergo:

  • A thorough health history and physical exam.
  • Genetic testing for hereditary mutations.
  • Routine blood tests along with a test for a specific tumor marker.
  • Blood and urine tests to help identify biomarkers to detect pancreas cancer at early stages.

If indicated:

  • Magnetic resonance cholangiopancreatography, or MRCP, a procedure that visualizes bile and pancreatic ducts.
  • A gastroenterology consult.
  • Endoscopic ultrasound.

Your costs will depend on your insurance coverage.

By participating in the program, you'll not only contribute to your own good health, but also to that of your family and future generations.

To see if you're eligible to enroll in the study, call 833-354-6667 or email us.