If you've ever had mono, short for infectious mononucleosis, you probably remember its classic symptoms well: exhaustion, malaise, sore throat, fever and more. While these can be a nuisance, is getting mono serious?
Yes, and no, said John Bigler, DO, an HonorHealth family medicine physician.
While most people who contract mono won't have any complications, some will. If the Epstein-Barr virus causes mono, there usually aren't any serious or long-lasting medical problems. If you have a compromised immune system and catch mono, you may have more severe symptoms than the average patient. Serious complications of mono may include:
- A ruptured spleen
- Guillain-Barre syndrome
- Cranial (head) nerve palsies
- Fatigue that persists for several months
Although it's uncommon, certain lymphomas have an established link to the Epstein-Barr virus. A correlation with chronic fatigue syndrome has been suggested, but the association is not well established. Other long-term conditions could occur, depending on areas affected by the initial infection.
"Because your spleen may become enlarged when you have mono, you should avoid sports and other physical activities that might put you at risk of a blow to the body," Dr. Bigler said. This will help safeguard you against a ruptured spleen.
The immune system typically clears mono without any persistent symptoms. If you have disease, you'll always have antibodies to whichever virus caused it in the first place. This means you can't get the same kind of mono more than once. You can, however, get mono again from a different virus that can cause the syndrome.